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The protective role of Nrf2 in STZ-induced diabetic nephropathy
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diabetesjournals-org
Objective: Diabetic nephropathy (DN) is one of the major causes of renal failure, which is accompanied by production of reactive oxygen species (ROS). Nrf2 is the primary transcription factor that controls the antioxidant response essential for maintaining cellular redox homeostasis. Here, we report our findings demonstrating a protective role of Nrf2 against DN. Research design and methods: We explore the protective role of Nrf2 against DN using human kidney biopsy tissues from DN patients, a s...
Reproduced under the Fair Use exception of 17USC107
year ago
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